I noticed a lot of things that felt like parallels to the game SOMA. If you haven't played SOMA, please go in and play it blind instead of reading this.
In the Romulus, one of the plots that unfolds throughout the movie is about an artifical human named Rook. It seems as if Rook has been left alone to his own devices. Rook becomes obsessed with making this goop that can "enhance" human life by letting them stay alive and be stronger. However, much like the WAU in SOMA, this goop doesn't really bring things back to life, or well, it creates things which are unrecoginizable from its former self. Although we see this all throughout SOMA, we learn how it works in both the movie and the game in the exact same way. In the game, Simon finds a dead rat in a lab, the rat can be injected with the WAUs weird goopy stuff, which "reanimates" the rat in its own weird gross terrible way. In Romulus, the characters enter a lab with a dead mutant rat, although the characters don't inject the rat, there is a video playing on the monitors showing the rat being killed, then reanimated, then eventually transformed into a freak of nature.
Another plot in Romulus and SOMA is questioning the morals of artificial humans and what really makes us human. In SOMA, the player is asked a lot of questions, does it matter that humanity lost its physical form? All that is left is digital copies of brains. Is it okay to hurt something if it is artifical? Even if it can express its pain? Even if it cries? While it is not as large of a focus in Romulus, one of the main characters is an artificial human named Andy. Throughout the movie, we see a wide array of opinions on artifical humans. From people who think they're terrible objects which have no emotions, to Rain, who deeply values Andy and views him as a brother. Although Andy is artificial, he expresses emotion which often looks like is being held back. Although we see a shift in Andy's personality when a new chip is put into his head, what we see doesn't seem to be Andy. It appears to be another mind controlling Andy, using him as a vessel. Which in a way, raises the question once again, should we value digital minds? Even if their origin isn't that of a naturally born human?
I dunno. I just thought it was neat. I am no essay writer, I just wanted to share my thoughts.